WATERS Autospec 6F

A piece of history: The AutoSpec 6F mass spectrometer is a large, floor standing instrument comprising a pair of commercial EBE geometry (AutoSpec) mass spectrometers coupled in series to provide an hybrid EBE-EBE configuration, (E and B being respectively electrostatic and magnetic sectors.) It has been designed in close collaboration between Professor R. Flammang and VG Analytical in Manchester, UK. It is equipped with five collision cells and allowed the recording of high energy CID (collision induced dissociation), MIKES (mass analyzed ion kinetic energy spectrometry) and NRMS (neutralization reionization mass spectrometry) data as well as consecutive MSn analyses. The field-free regions between sectors allowed the study of unimolecular decomposition products from long-lived metastable ions. The mass spectrometer became even more versatile when an RF-only quadrupole collision cell was installed between the second and the third electric sector. This allowed the study of associative ion/molecule reactions in the low kinetic energy regime. Bimolecular chemical reactions are performed inside the quadrupole cell when a neutral reagent is introduced and the reaction products were analyzed by high energy CID in the downstream sectors. This mass spectrometer arrived in the lab in 1990 and is still in operation.

Analytical capabilities: Electronic (EI) and chemical (CI) ionizations / Direct introduction of solid and liquid samples / Accurate mass measurements (HRMS) / Collision-induced dissociation experiments (keV)

Typical references:

1° “Gas Phase Ion Chemistry and Organic Chemistry: the story of a hybrid six sector mass spectrometer – the “AutoSpec 6F.” Pascal Gerbaux, Luc Lamote, Yves Van Haverbeke, Robert Flammang and Jeffery Brown, Eur.J.Mass Spectrom., 18 (2012) 93-112.

2° “Traces Do Matter – Purity of 4-Methyl-2-Oxetanone and Consequence in Anionic Ring-Opening Polymerization Evidenced by Phosphazene Superbases Catalysis.” Michał Kawalec, Olivier Coulembier, Pascal Gerbaux, Michał Sobota, Julien De Winter, Philippe Dubois, Marek Kowalczuk and Piotr Kurcok, Reactive and Functional Polymers, 72 (2012) 509-520.

3° “Poly(ethylene imine) impurities induce n-doping reaction in organic (semi)conductors” Simone Fabiano, Slawomir Braun, Xianjie Liu, Pascal Gerbaux, Mats Fahlman, Magnus Berggren and Xavier Crispin, Advanced Materials,  26 (2014) 6000–6006.